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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '627b35c8dec30e10268a7ebc3744831f9a2cf209bcbeff0c1deb03127dc96766' 
  AND token = '7lEUsa28X2h104+2tn+/N8axkeOJIdGi6MshYQSAAeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}