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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0427ee497afbda46e9273d3affbaeb0470bd1531f811c3b6259331ade5d07f34' 
  AND token = 'XIkzfDzDtFkY/CxNagUzPgiCrChyZOU1wPtI/unr8MQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}