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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b07420b419ca27d1d171aab541fdfc4b0f737c2cccebd005228613ad401fa566' 
  AND token = 'VT7tNX+8BvdQvF5Esfm3KQLa7+vZoHvKWpgfSV0fGro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}