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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bfbb180c944386b9c2dc772efa58c52f2a4fb7197fdaab9c11b3e6cd50b94b2' 
  AND token = 'S+VhXMveCzPbwe2QGeLOROe2hL7tltwOvSL3xzS0OZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}