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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '210d92542b6071e607fb04aa15a3a890aef737fe1af48da0bd8220280f2dc06c' 
  AND token = 'gZTjzPGbyMQl5CVX3V2ZtBa/eUQfawosDoHd3ntDm8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}