SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b1195568c33a28ae0a5579da28c37c59eb588f825fa9d382785093403fae97c' 
  AND token = 'c/lijkbOTOnVVcqdkDkzZFDS8B+WUpzhHnowRchAbLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}