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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46443b51d31dfec7c272c8cee4a21b886adaa5e40d9e31807d18fbde47c9be84' 
  AND token = 'WO9wDrh8AIVeFzt/L+UYMre9yzWsmeg7ETzUpYFMrlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}