SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2baed88bb93cc79a9950a29ab622543c5a6711df057ab14d0781c56e8228b1a5' 
  AND token = 'U5f/c46etAIaH4mlFE7bkepslgsppDqU+EFzFJZ0Tzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}