SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59e7f452febe9e4053bdcadb291a1cf351c8799168474ba56b8be25c810d7e22' 
  AND token = '8Z3SAn5iI4RjyPK7puKCs0Hl3a0VsM71A2zPJzL4iaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}