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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '603417ad62f53c08c38fe84cd00ebd622fe437710261430487868de7245c331c' 
  AND token = 'awyOqpSR4FFbU8rrJ4AnH2vs54RQ3WZ18UsEd5c7D7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}