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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82253951211e10fa091524efda63671e2b724331a47f62f6bd58d5293034f378' 
  AND token = 'jW7U7yCvvVwxShxi5o7fifyFMA1XAvhTWcHHwi70Umc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}