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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e434a10378e18b7de3c85cee1c67993861bc3f1dac4c635507087f8912168d7' 
  AND token = 'qoOBKEP5HWvx+H0VqTPTXFqaNrTnR7dGUNEC/atSlO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}