SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5aec7e018da680679cbbbf8513a9d2cbd01c70032bc49713b7f56851b78b82b9' 
  AND token = 'YtrwlTpUsX9z/f/zoDDmoWdECjMAUlpoF8avczukN/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}