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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fc46216fd707c115bb3f6be9da54c0e712fe5eaa2e29f1d04c79fa8455ccd39' 
  AND token = '9ywuyA1PTFPytxxkg6dlGId+CmFLaStjzxL+DKM0xIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}