SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '289b90fd1281c72748ee63ace0409d8f3fdfd631d10a25c2d5281bdf0b5bc0bb' 
  AND token = 'EJL8BN1TQFw6KdeiTJL6cWP5bfrJF71T9vF7ip2H5as=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}