SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b428411261d040e5fa9af107e25be8fc55c9a2e1a6d7a86842755144042499b7' 
  AND token = 'I+bT+Zt7fj8PKLBekIwETuKXDRR+A0SKh8q3OiUHB/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}