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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfaed3580b9c47e601dc858bc1560165b442bdbf268d0801a5441eb215acd565' 
  AND token = 'F3Cf71z0VBjjcOnoFY/ZvUjIxATQ/4X2ocjG6lIng/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}