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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02001ba60f4cda1c8acc906042948cdd99d8a610c8db37e47e1e5a41591a5b51' 
  AND token = 'zDI1L21Z53d68L03VqW/SgOTXtt8UZtOxON3GnEngUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}