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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '494b29f40003bfc0eec7349cf5d6aa34f9cba5622e07715e62d7c54380b19030' 
  AND token = '/0z9ET55LmlGhd3pUreQvEEYNwdweGNMK5zlRn7lb2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}