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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f505d46b30bef6bd8831467a615adc62f9247a687f274e82d939df15da583f3e' 
  AND token = '+ZjMQ7+yZ4+oOWCKvkH5nf08aVP8uA1gArMNOEzyvDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}