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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8c4e977d75254473312d0dc7b8bd02c416a6360a366333ba54e56e1d1fa2432' 
  AND token = 'apkhX4S1uWtTgfJv+2EXSR0fKsk4NAwlBzzmNqqfTFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}