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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d7e9ea4725f73d2a07c35e851955809bd3d21c5695cfbc4f386ba363085e5e4' 
  AND token = 'e6vJ7WEb++JrF0WcEzKJjtF57VAbDDpUB2V/7HPaf5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}