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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75bfffcb78cc922c9d5e7156d12ed9bed53d179c55f8dc276fcbb13272117aec' 
  AND token = '1RFEZkVdC9F8r7yTd7t0pYSj3ohHt+b3T+PvMQjTiVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}