SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65969b80cb9e1e5a5826c356e3613797fff9d0c73a5987a2cb45484e94dac172' 
  AND token = 'RbOdKZl9zjUgO/I5L0c7N7veVi03ry1phQWmjzTJrXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}