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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aa86632a7d2ebd0a13852fa644c442fc2bda2188b30f87a40c09b096f50c724' 
  AND token = 'yOp/T1KgoJsyqQthhzaUO8mCrXsUJwFobil8wDFpoAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}