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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8655b845e7b5b4968bc4ccb37f638b0955e18331c7c761bd39b0700d5bc7621c' 
  AND token = 'RTysO2L4OTRyErRxr0I2r+hB+QfNFO+Mv/d+quKzXrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}