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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3d5eddc0c132a3a06bb6020e9a7f22915b27dfdc592b08b2b4cfadcbe6a2047' 
  AND token = 'vCpl0+pX+jYkDhWfLlP2p6DCa8QJfd0c6WR7xIsRTFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}