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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b024f4c8f55e62c5e06f8f4363ad5490255801659919700afae5370f2cb710a9' 
  AND token = 'UmBaskG1T2M4acabqOk+efEVu7X8PeV+gwCJu2hyXKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}