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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b48d1ce8b88c57c01182fa53191f9ba219ad4ee9c69bf1645aa8a8fe977461a5' 
  AND token = '167SUTGZwqNW7C/sjv6qGd7OKkA2iGMtgp9Nu7mfKCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}