SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de44e9285406bab4c578e316f2cdff75b86e9fd192a2ca668e2d2b00e9769758' 
  AND token = 'X1DQCfX0KhAZmc6bCBwjoIT0JiVfx54tbpsBGfvgkHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}