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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e660c3e4c5587162fb00f8aac3e56ac5ecac361308bb2fbb434fdfcbf4b90245' 
  AND token = 'CFYhOLXxlh8lPKvb4fpj31QlIpzSY0foLBHiCrZ3i0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}