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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ed4b4d5553d73897083fd004799ef48734780c8f65d159da2e22c3f2e073a81' 
  AND token = 'lus4YZUgmFpr664Ncv3Ag37H5oF4uUV3SkKTALsVaOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}