SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10708f1fda272b152b5a3a7046d80196ca13a57695821c3f22cfac13d366f58a' 
  AND token = 'wicHJRj78oQqAsNLakNUBb2LaDBS9RHxluTJpMw0EdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}