SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a0de54452716f5ca84252c27e47338dac86c858161f29680411b5e42255361c' 
  AND token = 'WSsusiiZiRxNfynY6WdI5aIdHjeyCEcjFPb69XUvhwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}