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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77c661581fe0eee312fb8f8f4e2d9322ebf6594b6918fd88c9b25fc551017f4d' 
  AND token = 'T/N8vYZ2Btg2aGb4tNdeCIyFpldo3wzIWqOkUS7F9BA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}