SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3f4750e874a91177caf560119383a37127a3717af5f939177b1589b07944944' 
  AND token = '9Rzpx2+7d/Agi7gBhBWi4Ek+rKTHYw3DrNIJGWeixc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}