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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21c2e9fee727c267b68631f622a6d1af01bc2c9a8143b789f8048592b46c7780' 
  AND token = '/xvF0PCMiYd/LSOK82UnlxKi53WqIRr79PtqGaJxD/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}