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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eca351431f124547892e5c99130cf45628d373b0f1832ffadb5944d72b68d2d' 
  AND token = 'ne4Iy4nqweEJfaWzaOfha5ZQ03hGw6G0uAO8ToGZtwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}