SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dc023656dfcb1ed1b5d42b69fc9823f6bc08e605f320a635d842ce5d8f11b0e' 
  AND token = 'T+woMwU4VEn2H+/dCqDFTsD4E7cW1IN7h+DipMnXWmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}