SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd45bad33b772138419755a6cbde92252720e47a3a02713355f1ac0d4cb65467e' 
  AND token = 'D/fDbH1s+VIY1tAPFjiAGpCIxu9Yh2OdOqSz3/hS5fI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}