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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67b5a3a0d478a7bb6649137abab11fc3d50e71427b9ef824aae1d1d94e1ad6a5' 
  AND token = 'hfKqLVMEEgnd0YgEGRPaGEOylMgUB6U5X95MkycXr28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}