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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '083a41367d3edfdb6c14fc3827ea9dff7f54031212d9bc07e405d7e278f568f4' 
  AND token = 'LuuX/S4F6yIQSvqWA+ToJo2qus6fsEgWvR4p6z0XWiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}