SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54725faf463b7540ecb31c89d0a1cafc4ad7f304af8aff37c2234eba56a8a3d0' 
  AND token = 'MOnP7+qL/QhxyR8wX7eBY0TH9NhM1jHXlDfIRjKDVDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}