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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e49772748f079780b10d4836e1c354be293ae03db263917609a3726b2e611ea8' 
  AND token = 'VzI9dAOwmi4+R+Kac05/PQFdqBvbQSUBT5Y2b1WY50E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}