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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3f696541e4a462b0984a3ee208a2462248c1c3df31f538bd53ff08f71c3ba18' 
  AND token = 'dJCb2IQ1NYpvYXtXbAi1pAxziI6z+uW7RPwQsaAtt2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}