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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8774265d21aff37258c5d337e57c6ba78968a3b41044e24fe7d516372412bd3' 
  AND token = 'OvWUz4uA+1rYYUrzCRsITfW2/0lN7dJaFYngRO9UaPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}