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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd000edf77698daa791b961532f432775fa0602acccf3d14582e527fc1efcce1f' 
  AND token = 'RsJFeDPCqjUZ2LT6Ok8vmY8r1MFvyT3kQnaSah76FKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}