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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '150b88ebb99cc39d4345a4678a84ccd841419c3f7b068df84f57a41bfbd6e494' 
  AND token = 'r7M+S/3ezJ9/HoWX8oyD2hKs3iRWHg1sqcMdZxBZ++k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}