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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c9a49ad6b39400a8e094efb8bb9b14e1a28435ddad7cfbda1e9edf863e5f8d3' 
  AND token = 'Xptjwwued4INA5EsOQDRdhDql+2LlkTllZcq6ntZpS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}