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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8852bd75d4b48931b7f7654807d9c3014583585f3e66efd7f7af8fdd6a0d0005' 
  AND token = 'e9rB0C98KQ9mKd+h8waW4eYeL7l8S1unODWkBPlZZUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}